L’azithromycine, commercialisée sous le nom de Zithromax, est un antibiotique macrolide dérivé de l’érythromycine mais doté d’une demi-vie plus longue et d’une meilleure tolérance digestive. Son mécanisme repose sur l’inhibition de la sous-unité 50S ribosomale, bloquant la translocation peptidique et interrompant la synthèse des protéines essentielles. Sa pharmacocinétique est caractérisée par une absorption digestive rapide, une distribution intracellulaire élevée et une élimination biliaire prédominante, ce qui prolonge son activité même après la fin du traitement. Dans la littérature clinique, l’efficacité de l’azithromycine est confirmée dans les infections respiratoires basses, les infections à Chlamydia trachomatis et certaines pathologies ORL. Les sources spécialisées indiquent également que zithromax prix est mentionné dans le cadre d’un usage rationnel, avec une vigilance accrue concernant les interactions avec les antiarythmiques et le risque d’allongement de l’intervalle QT.
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To be clear, Amazon's customer service and the sellers service were excellent, but the product itself was SUCH a disappointment. I regret not having been more thorough in reading the good AND bad reviews of this vacuum BEFORE I purchased it - turns out the issue I had was pretty common; the thing overheats so quickly and will cease to roll/suck until it cools off (20 minutes of wait time for another 5 minute session). Reasonable safety measure I agree, but bombing out at the 5 - 7 minute mark is absurdly annoying and ineffective! If I was challenging the vacuum I could understand, but my situation is within normal usage - carpet is berber and pretty well taken care of with multi-vacuuming sessions a week and a steam cleaning quarterly, so it's not like the Shark had 8 months of filth to try and fight through.
This is the second Gilmore hose we purchased this year from Amazon and so far it has not kinked and works fine. Not too heavy to pull around the yard either. I took the 5/8 inch for extra durability and I do believe that was a good choice. Price was reasonable for this hose. Great buy!